The dissimilar joining of Ti6Al4V titanium alloy and NiTi shape memory alloy has attracted considerable attention for applications in aerospace adaptive structures and biomedical devices， where high specific strength， corrosion resistance， and shape memory or super elastic functionality are simultaneously required. However， pronounced differences in thermophysical properties， phase transformation behavior， and chemical reactivity between the two materials make the joining process highly susceptible to interfacial defects， the formation of brittle Ti-Ni intermetallic compounds， and degradation of functional performance， thereby limiting engineering applications. Focusing on the representative Ti6Al4V/NiTi material system， this paper systematically reviews recent progress in conventional welding and additive manufacturing techniques with respect to interfacial microstructural evolution， defect control， and property tailoring. The interfacial reaction characteristics and their effects on mechanical performance and shape memory behavior are analyzed， key common challenges and corresponding mitigation strategies are summarized， and future research directions toward aerospace and biomedical applications are discussed.