In a wind tunnel test， the tail model support system of cantilever beam structure will produce vibration under the wind load， which may threaten test safety and affect test results. In order to suppress the vibration of the model and support system， an active vibration control method is studied and applied. Among them， the actuator of suppression system adopts piezoelectric material， and the control system is based on adaptive internal model control algorithm.This paper analyzes the structure and working principle of the adaptive internal model control algorithm， and introduces the model parameter identification in training mode and the adaptive adjustment process of control parameters in experimental mode. A control system based on the adaptive internal model control algorithm is established. A signal generator is used to simulate the excitation of the system on the ground simulation platform. The control algorithm is verified as the input of the control system. Combined with the wind tunnel test， the control effect of the system is verified under actual conditions. The results show that the active vibration control system based on adaptive internal model control algorithm can reduce the vibration by more than 70%.