Aiming at the problems in the assembly process of large antenna, for example, the spatial location of coaxial hinge is difficult to adjustment accurately, and the measurement accuracy of traditional measurement methods is affected by the interference of antenna poles. The paper builds the system of assembly measurement and real-time feedback adjustment for large antenna. The assembly accuracy of antenna hinges and poles are measured by digital photogrammetry. The measured results are feedback to the 6-DOF automatic actuator to adjust the spatial location of coaxial hinge, thus the automatic assembly of large antenna can be realized. Experimental results show that the measurement accuracy between the digital photogrammetry and laser tracker is no more than 0.01 mm; the displacement accuracy of the 6-DOF automatic actuator to adjust the spatial location of coaxial hinge is better than 0.02 mm, and angle accuracy is better than 0.01°. It can meet the assembly and measurement requirements of large antenna. The method can improve the assembly efficiency and automation level of large antenna. It lays technology foundation for antenna assembly with larger size and more complex structure.