According to the characteristics of the rapid increase in the data processing for the satellite borne processor, a new method based on SERDES technology for high-speed transmission is proposed. Based on the principle of SERDES Serializer/Deserializer, the method adaptively adjusts the SERDES input parameter, and solves the problem of phase shift inherent in high-speed serial data transmission between FPGAs at different temperatures. Experimental result shows that the method can achieve the reliable data transmission of 333 Mb/s of 78 channels at the temperature range of -25℃ to +60℃, which meets project requirement and is transplantable. The research in the paper provides a wide application prospect in satellite high-speed data transmission.