In view of the poor machinability of turbine blade root made of directional solidified nickel-based superalloy DZ125, high efficiency deep grinding(HEDG) process is conducted to analyze specific grinding energy and surface integrity with profiled electroplated CBN grinding wheel. The result shows that higher grinding speed vs can lower the specific grinding energy effectively when the speed ratio (vs/vw) keeps constant. The specific grinding energy decreases with the increasing mean material removal rate and finally remains in range of 40—60 J/mm3. Under the same mean material removal rate, the specific grinding energy increases with the decreasing depth of cut. However, the difference of depth of cut has little effect on the specific grinding energy with the same undeformed chip thickness. The surface quality of the workpiece obtained under the highest mean material removal rate is analyzed. The surface texture is clear, and does not present wrinkles and ploughing marks. The phase transition and grain distortion are not observed from the metallographic microstructure. The degree of work hardening is in range of 7.7%—19%, and the hardening depth is about 40 μm. The result reveals the potential of HEDG in the high efficiency machining of turbine blade root DZ125, and provides reference for future application.