As the flow temperature rises dramatically at high altitudes and hypersonic speeds， the thermodynamic properties of gas change， causing changes in aerodynamic properties of waverider. Therefore， it is of great engineering value to investigate real gas effects in the design of waverider. A method of characteristic （MOC） considering equilibrium gas effect is proposed for the design of cone-derived waverider. Different shapes of waverider are generated based on different half cone angles and different flow capture curves， and the aerodynamic and geometrical characteristics of each waverider under equilibrium gas and perfect gas conditions are estimated using a fast estimation method. The results shows that there are differences in the lift-to-drag ratio， volume ratio and pitch moment coefficient of the waverider designed based on the equilibrium gas model at high Mach number compared with the perfect gas results. The degree and pattern of the influence of equilibrium gas effect on different configurations of waverider are distinct.