In order to improve the overall cooling effectiveness of a specific transverse wavy shield， we investigate the optimization of structural parameters of effusion cooling configuration. It is under a fixed coolant mass flow rate per unit area on the film-cooled surface， by using three-dimensional numerical simulation and support vector machine（SVM）-based surrogate model approximation. Three design variables are selected as film-hole diameter， streamwise hole-to-hole pitch and spanwise hole-to-hole pitch of an effusion cooling array. The genetic algorithm is used to search the optimal design point among the ranges of design variables， selecting the area-averaged overall cooling effectiveness as the objective function. Under the condition of G_f = 2.647 kg/（m²?s） ，the optimized d， P and S are 0.8，4，5 mm. The results show that the optimal cooling configuration of this transverse wavy shield has a smaller film-hole diameter， a smaller spanwise hole-to-hole pitch and a moderate streamwise hole-to-hole pitch. With respect to the reference cooling configuration， the optimized cooling configuration improves the film coverage along the streamwise direction and shortens the length of effusion-cooling initial developing zone with high temperature. As a consequence， the overall cooling effectiveness on the transverse wavy shield is enhanced.