Wing structures with multiple plug-ins should meet the requirements of strength, stiffness, aeroelastic and assembly of equipment, it is difficult to get the optimal solution with traditional methods. In this paper, an analytical method is proposed to control the aeroelastic characteristics of the wing by restricting the bending and torsion stiffness of the wing section. The displacement and stability constraints sensitivity theories have been researched simultaneously. Then the new multi-constraints optimization process is developed and programmed based on the HAJIF platform. The method is verified by using a real wing model, and the results show that the proposed method can give the optimal design scheme on the unique static analysis model while the strength, stiffness and stability constraints are considered synchronously.